What changed

272 changes recorded since monitoring began on 2026-08-21, of 6 different kinds. This is the page that cannot be reconstructed anywhere else: ClinicalTrials.gov and the FDA shortage database both overwrite a record when it changes, keeping no public history of what it used to say. A completion date moving out by two years, a phase 3 trial quietly changing status, a presentation flipping to discontinued — each is invisible the day after it happens unless something was watching. Each row below carries the previous value alongside the new one.

Six times a day we snapshot the registry and compare it to the previous one. When a company quietly pushes a reporting date back, halts a trial or resizes an enrollment, ClinicalTrials.gov shows the new value and says nothing about the old one. So we keep the old one. Changes marked lead are phase 3 movements of six months or more, or phase 3 halts.

Take the whole archive: changes.json or changes.csv, rebuilt with the site and documented in the JSON itself. Entries marked new are first sightings rather than changes, and previous is empty where this site never saw an earlier value. CC BY 4.0 — cite GLP-1 Briefing and use it for anything.