What happens next in GLP-1 — and when.

Get the briefing

What moved in the GLP‑1 field, in your inbox.

@glp1briefing

Trial results

Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes

NCT07685808 on ClinicalTrials.gov · last registry update 2026-08-20

An unusually large phase 2: 360 participants, more than double the 114 typical for the stage. Due to report 21 January 2028, alongside 22 other tracked readouts that quarter. Primary outcome, as filed: Occurrence of Treatment-Emergent Adverse Events (TEAEs). Sponsors move these dates routinely; any movement since this site started watching is listed below. olatorepatide is not approved in the US for anything yet, so this is a drug in development rather than an established treatment being extended. The registry entry has been edited 1 time since then.

Status
RECRUITING
Phase
P2
Drug
olatorepatide
Sponsor
Regeneron Pharmaceuticals
Sponsor type
Industry
Enrollment
360
Started
2026-07-28
Primary completion
2028-01-21 estimated

Observed history

Every change this record has made since we started watching it. ClinicalTrials.gov shows only the current value. When a field is edited the previous one is overwritten and nothing is published to say so, so this history exists only because someone was recording it at the time.

DetectedChangeDetail
2026-08-21First seen in registryRegistered as RECRUITING, P2

Primary outcome

Occurrence of Treatment-Emergent Adverse Events (TEAEs)

Conditions studied

Overweight or Obesity

Every field above is taken directly from the registry record. See all detected changes across the class, or the olatorepatide page for this molecule’s full trial and approval history.