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Pipeline › olatorepatide

olatorepatide

Not FDA-approved, and in phase 2 development, not authorised in the European Union. 2 active trials, the next due to complete 2026-11-13.

incretin (auto-detected) agonist, unknown, from Regeneron Pharmaceuticals. Every figure below is taken directly from ClinicalTrials.gov, Drugs@FDA, the FDA Drug Shortage Database, the EMA register or Europe PMC, and re-checked every four hours.

Status
phase2
Target
incretin (auto-detected)
Route
unknown
Sponsor
Regeneron Pharmaceuticals
First FDA approval
Not approved
EU authorisation
Not authorised
Active trials
2 (0 in phase 3)
Participants enrolled
480
Trials with a reporting date
2
Approved FDA submissions
0

Recent changes

DetectedChangeTrialDetailPhase
2026-08-21New trial registeredStudy of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
NCT07685808 · Regeneron Pharmaceuticals
Recruiting, n=360P2
2026-08-21New trial registeredStudy of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US
NCT07431086 · Regeneron Pharmaceuticals
Active, not recruiting, n=120P2

When these trials report

01Q3 26: 0 trials reportingQ4 26: 1 trial reportingQ1 27: 0 trials reportingQ2 27: 0 trials reportingQ3 27: 0 trials reportingQ4 27: 0 trials reportingQ1 28: 1 trial reportingQ2 28: 0 trials reportingQ3 261Q4 26Q1 27Q2 27Q3 27Q4 271Q1 28Q2 28
When trials are due to report, by quarter — hover a bar for the count. These dates are filed by the sponsor and often move.

Next 2 of 2 active trials by estimated primary completion.

Est. completionTrialSponsorPhaseParticipants
2026-11-13Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US
NCT07431086 · Occurrence of Treatment-Emergent Adverse Events (TEAEs)
Regeneron PharmaceuticalsP2120
2028-01-21Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
NCT07685808 · Occurrence of Treatment-Emergent Adverse Events (TEAEs)
Regeneron PharmaceuticalsP2360

Indications under study

Overweight or Obesity.

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