What happens next in GLP-1 — and when.

GLP-1 pipeline, trials, approvals and supply.

Taken directly from public records and refreshed multiple times daily: what is in development, when trials are due to report, what the FDA and EMA have decided, and what is in short supply. The news section follows headlines from the trade and business press. My Journey is where I write about taking one of these drugs.

ClinicalTrials.gov · Drugs@FDA · FDA Drug Shortages · EMA · Europe PMC · Federal Register

Trial results calendar
202 scheduled
Every active phase 2+ trial with a sponsor-filed completion date. 22 land in the next 90 days.
What changed
Checked every four hours
We snapshot the trial registry and compare it to the last one. When a company quietly pushes a date back or halts a study, the old value is kept here.
Pipeline
22 molecules
Marketed and investigational incretin and amylin agents, with 167 active phase 3 trials behind them.
Regulatory
299 FDA actions
Approvals, efficacy supplements and labeling changes — where new indications and safety language actually land.
Supply
14 live records
FDA shortage and discontinuation entries. Supply status is what drives compounding eligibility.
Research
335 papers
Newest peer-reviewed work and preprints naming a tracked molecule.
Next results due2026-10Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)retatrutide · P3 · Eli Lilly and Company

Latest headlines

2026-10-16Two people have died after taking bootleg versions of not-yet-on-the-market ‘triple G’ weight loss drug
New York Post
2026-10-16The Difficulty of Diagnosing Anorexia in the GLP-1 Era
The New York Times
2026-10-16The Oral GLP-1 Tracker: Foundayo, Wegovy pill undergo minor fluctuations
Fierce Pharma · orforglipron · semaglutide
2026-10-16GLP-1 Agonists Address Metabolic Risk in Psoriatic Disease
Dermatology Times
2026-10-16What to Know About the GLP-1 Pill Orforglipron
Medscape · orforglipron
2026-10-16Indore Company Gets Patent For Supplement It Says Can Fight Muscle Loss From Weight-Loss Drugs
Republic World
2026-10-16Why health plans should rethink GLP-1 coverage
Medical Economics
2026-10-16I Tried GLP-1 Supplements for a Week. I’m Still Hungry. - Bon Appétit: Recipes, Cooking, Entertaining, Restaurants | Bon Appétit
Bon Appétit: Recipes, Cooking, Entertaining, Restaurants | Bon Appétit
More headlines →

Recent changes

2026-10-15semaglutide: results date moved
A Study of BGM0504 in Participants With Type 2 Diabetes
2026-10-13semaglutide: results date moved
A Study of BGM0504 in Participants With Type 2 Diabetes in Indonesia
2026-10-13semaglutide: enrollment changed
A Study of BGM0504 in Participants With Type 2 Diabetes in Indonesia
2026-10-13semaglutide: results date moved
Semaglutide for Helping Opioid Recovery
2026-10-13ecnoglutide: status changed
A Study of Weekly Oral Dose of Ecnoglutide (VRB-101) for Weight Maintenance in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
2026-10-09VK2735: new trial registered
Oral VK2735 for Weight Management in Adults With Type 2 Diabetes Mellitus Phase 3 (SUNRISE 2)
All changes →

Reporting in the next 90 days

22 trials reach their scheduled completion date within 90 days, 13 of them phase 3, 8,544 participants between them. Dates are filed by the sponsor and move often. Each one links to its own record and change history.

2026-10-31Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes
semaglutide · P4 · The University of Texas Health Science Center, Houston · n=300
2026-11A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity
tirzepatide · P3 · Eli Lilly and Company · n=800
2026-11A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight
tirzepatide · P3 · Eli Lilly and Company · n=465
2026-11A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight
tirzepatide · P3 · Eli Lilly and Company · n=905
2026-11-13Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US
olatorepatide · P2 · Regeneron Pharmaceuticals · n=120
2026-11-14A Study of BGM0504 in Participants With Type 2 Diabetes
semaglutide · P3 · BrightGene Bio-Medical Technology Co., Ltd. · n=537
2026-11-20Study to Evaluate the Effect on Obesity of QW Nimacimab and QW Nimacimab Co-administered With Semaglutide vs Placebo
semaglutide · P2 · Skye Bioscience, Inc. · n=136
Full results calendar →

How this works

Primary sources only

ClinicalTrials.gov, Drugs@FDA, the FDA Drug Shortage Database, the EMA register, Europe PMC and the Federal Register. Every field is taken directly from a source record and links back to it.

Refreshed every four hours

The whole set is re-fetched six times a day and the registry is diffed against the last snapshot, so a date that quietly moves is caught within hours instead of vanishing.

Not medical advice

This is a news and data tracker. No dosing, no treatment guidance, and no efficacy claims that aren’t attributed to a named study.

Method

Sources, editorial policy and how each page is built. Read the method →

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