What happens next in GLP-1 — and when.

Trial results

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

NCT07668414 on ClinicalTrials.gov · last registry update 2026-09-28

Recruiting now, toward 650 participants. Due to report 10 October 2028, alongside 27 other tracked readouts that quarter. Primary outcome, as filed: Relative change in body weight. Sponsors move these dates routinely; any movement since this site started watching is listed below. semaglutide is already approved in the US for obesity, so this is asking a further question rather than establishing the drug works at all. The registry entry has been edited 1 time since then.

Status
RECRUITING
Phase
P3
Drug
semaglutide
Ozempic, Rybelsus, Wegovy
Sponsor
Novo Nordisk A/S
Sponsor type
Industry
Enrollment
650
Started
2026-09-22
Primary completion
2028-10-10 estimated

Observed history

Every change this record has made since we started watching it. ClinicalTrials.gov shows only the current value. When a field is edited the previous one is overwritten and nothing is published to say so, so this history exists only because someone was recording it at the time.

DetectedChangeDetail
2026-09-28Status changedNOT_YET_RECRUITING → RECRUITING

Primary outcome

Relative change in body weight

Conditions studied

Overweight · Obesity

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.

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