What happens next in GLP-1 — and when.

Get the briefing

What moved in the GLP‑1 field, in your inbox.

@glp1briefing

Pipeline › VK2735

VK2735

Not FDA-approved, and in phase 2 development, not authorised in the European Union. 2 active trials, the next due to complete 2027-07-01.

GIP/GLP-1 agonist, SC/oral, from Viking Therapeutics. Every figure below is taken directly from ClinicalTrials.gov, Drugs@FDA, the FDA Drug Shortage Database, the EMA register or Europe PMC, and re-checked every four hours.

Status
phase2
Target
GIP/GLP-1
Route
SC/oral
Sponsor
Viking Therapeutics
First FDA approval
Not approved
EU authorisation
Not authorised
Active trials
2 (2 in phase 3)
Participants enrolled
5,600
Trials with a reporting date
2
Approved FDA submissions
0

When these trials report

12Q3 26: 0 trials reportingQ4 26: 0 trials reportingQ1 27: 0 trials reportingQ2 27: 0 trials reportingQ3 27: 2 trials reporting, 2 phase 3Q4 27: 0 trials reportingQ1 28: 0 trials reportingQ2 28: 0 trials reportingQ3 26Q4 26Q1 27Q2 272Q3 27Q4 27Q1 28Q2 28
When trials are due to report, by quarter — hover a bar for the count. These dates are filed by the sponsor and often move.

Next 2 of 2 active trials by estimated primary completion.

Est. completionTrialSponsorPhaseParticipants
2027-07-01VK2735 for Weight Management Phase 3
NCT07104500 · Percentage change in body weight from baseline for participants receiving VK2735 after 78 weeks of treatment
Viking Therapeutics, Inc.P34,500
2027-07-01VK2735 for Weight Management Type 2 Diabetes Phase 3 (VANQUISH 2)
NCT07104383 · Percent change in body weight from baseline to Week 78 in body weight
Viking Therapeutics, Inc.P31,100

Indications under study

Weight Loss.

Recent papers

PublishedTitleJournal
2026-01-08Weekly Subcutaneous VK2735, a GIP/GLP-1 Receptor Dual Agonist, for Weight Management: Phase 2, Randomized, 13-Week VENTURE Study
Bays HE, Toth P, Alkhouri N, Pullman J, Freilich B, Neutel J, Ji S, Stubbe S, Hedges P, Lian B.
Obesity (Silver Spring)

Headlines

2026-09-02
Will Upcoming Oral VK2735 Late-Stage Trials Change Viking Therapeutics' (VKTX) Obesity Drug Narrative?
simplywall.st

Related