What happens next in GLP-1 — and when.

Trial results

A Neuropsychobiological Approach to Optimize Patient Selection for GLP-1-based Pharmacotherapy for Weight Management Across the Binge Eating Spectrum

NCT07870538 on ClinicalTrials.gov · last registry update 2026-10-13

Recruiting now, toward 96 participants. Due to report December 2028, alongside 27 other tracked readouts that quarter. Primary outcome, as filed: Change in Body Mass Index (BMI) after semaglutide treatment. Sponsors move these dates routinely; any movement since this site started watching is listed below. semaglutide is already approved in the US for obesity, so this is asking a further question rather than establishing the drug works at all. The registry entry has been edited 1 time since then.

Status
RECRUITING
Phase
P4
Drug
semaglutide
Ozempic, Rybelsus, Wegovy
Sponsor
Universitaire Ziekenhuizen KU Leuven
Sponsor type
Other
Enrollment
96
Started
2026-08-26
Primary completion
2028-12 estimated

Observed history

Every change this record has made since we started watching it. ClinicalTrials.gov shows only the current value. When a field is edited the previous one is overwritten and nothing is published to say so, so this history exists only because someone was recording it at the time.

DetectedChangeDetail
2026-10-13First seen in registryRegistered as RECRUITING, P4

Primary outcome

Change in Body Mass Index (BMI) after semaglutide treatment

Conditions studied

Obesity & Overweight

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.

@glp1briefing