What happens next in GLP-1 — and when.

Trial results

A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity

NCT07639021 on ClinicalTrials.gov · last registry update 2026-09-16

An unusually large phase 2: 233 participants, more than double the 110 typical for the stage. Due to report 14 June 2027, alongside 42 other tracked readouts that quarter. Primary outcome, as filed: Number of gastrointestinal adverse events. Sponsors move these dates routinely; any movement since this site started watching is listed below. semaglutide is already approved in the US for obesity, so this is asking a further question rather than establishing the drug works at all. The registry entry has been edited 3 times since then.

Status
ACTIVE_NOT_RECRUITING
Phase
P2
Drug
semaglutide
Ozempic, Rybelsus, Wegovy
Sponsor
Novo Nordisk A/S
Sponsor type
Industry
Enrollment
233
Started
2026-06-09
Primary completion
2027-06-14 estimated

Observed history

Every change this record has made since we started watching it. ClinicalTrials.gov shows only the current value. When a field is edited the previous one is overwritten and nothing is published to say so, so this history exists only because someone was recording it at the time.

DetectedChangeDetail
2026-09-16Status changedRECRUITING → ACTIVE_NOT_RECRUITING
2026-09-16Reporting date moved2027-07-12 → 2027-06-14 1 months earlier
2026-09-16Enrollment changed230 → 233 (+3) participants

Primary outcome

Number of gastrointestinal adverse events

Conditions studied

Obesity

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.

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