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Trial results

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

NCT06897475 on ClinicalTrials.gov · last registry update 2026-08-21

An unusually large phase 2: 240 participants, more than double the 114 typical for the stage. Due to report December 2026, alongside 33 other tracked readouts that quarter. Primary outcome, as filed: Change from Baseline in Hemoglobin A1c (HbA1c). Sponsors move these dates routinely; any movement since this site started watching is listed below. semaglutide is already approved in the US for type 2 diabetes, so this is asking a further question rather than establishing the drug works at all.

Status
RECRUITING
Phase
P2
Drug
semaglutide
Rybelsus, Wegovy, Ozempic
Sponsor
Eli Lilly and Company
Sponsor type
Industry
Enrollment
240
Started
2025-03-28
Primary completion
2026-12 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Change from Baseline in Hemoglobin A1c (HbA1c)

Conditions studied

Type 2 Diabetes

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.