What happens next in GLP-1 — and when.

Trial results

The Effect of Oral Semaglutide on Bone Turnover in Patients With T2D: a Randomized Placebo-controlled Clinical Trial

NCT06050577 on ClinicalTrials.gov · last registry update 2026-10-05

Closed to new participants; the 64 already enrolled are still being followed. Due to report 15 January 2027, alongside 31 other tracked readouts that quarter. Primary outcome, as filed: Procollagen type 1 N-terminal propeptide (P1NP). Sponsors move these dates routinely; any movement since this site started watching is listed below. It has been running since 7 June 2024 — 2 years so far. semaglutide is already approved in the US for type 2 diabetes, so this is asking a further question rather than establishing the drug works at all. The registry entry has been edited 1 time since then.

Status
ACTIVE_NOT_RECRUITING
Phase
P2
Drug
semaglutide
Ozempic, Rybelsus, Wegovy
Sponsor
Odense University Hospital
Sponsor type
Other
Enrollment
64
Started
2024-06-07
Primary completion
2027-01-15 estimated

Observed history

Every change this record has made since we started watching it. ClinicalTrials.gov shows only the current value. When a field is edited the previous one is overwritten and nothing is published to say so, so this history exists only because someone was recording it at the time.

DetectedChangeDetail
2026-09-21Reporting date moved2026-01-15 → 2027-01-15 12 months later

Primary outcome

Procollagen type 1 N-terminal propeptide (P1NP)

Conditions studied

Type 2 Diabetes · Osteopenia

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.

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