What happens next in GLP-1 — and when.

Trial results

The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect

NCT06058585 on ClinicalTrials.gov · last registry update 2026-10-05

An unusually large phase 3: 2,000 participants, more than double the 424 typical for the stage. Due to report 31 December 2029, alongside 7 other tracked readouts that quarter. Primary outcome, as filed: Core Primary Outcome Measure. Sponsors move these dates routinely; any movement since this site started watching is listed below. It has been running since 4 September 2024 — 2 years so far. semaglutide is already approved in the US for chronic kidney disease, so this is asking a further question rather than establishing the drug works at all. The registry entry has been edited 1 time since then.

Status
RECRUITING
Phase
P3
Drug
semaglutide
Ozempic, Rybelsus, Wegovy
Sponsor
The George Institute
Sponsor type
Other
Enrollment
2,000
Started
2024-09-04
Primary completion
2029-12-31 estimated

Observed history

Every change this record has made since we started watching it. ClinicalTrials.gov shows only the current value. When a field is edited the previous one is overwritten and nothing is published to say so, so this history exists only because someone was recording it at the time.

DetectedChangeDetail
2026-10-05First seen in registryRegistered as RECRUITING, P3

Primary outcome

Core Primary Outcome Measure

Conditions studied

Chronic Kidney Diseases

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.

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