What happens next in GLP-1 — and when.

Trial results

Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema

NCT07817251 on ClinicalTrials.gov · last registry update 2026-09-30

A small phase 3 — 210 participants, against a typical 424. Due to report 9 June 2027, alongside 42 other tracked readouts that quarter. Primary outcome, as filed: Number of treatment emergent adverse events (TEAEs). Sponsors move these dates routinely; any movement since this site started watching is listed below. semaglutide is already approved in the US for type 2 diabetes, so this is asking a further question rather than establishing the drug works at all. The registry entry has been edited 2 times since then.

Status
RECRUITING
Phase
P3
Drug
semaglutide
Ozempic, Rybelsus, Wegovy
Sponsor
Novo Nordisk A/S
Sponsor type
Industry
Enrollment
210
Started
2026-09-16
Primary completion
2027-06-09 estimated

Observed history

Every change this record has made since we started watching it. ClinicalTrials.gov shows only the current value. When a field is edited the previous one is overwritten and nothing is published to say so, so this history exists only because someone was recording it at the time.

DetectedChangeDetail
2026-09-30Status changedNOT_YET_RECRUITING → RECRUITING
2026-09-14First seen in registryRegistered as NOT_YET_RECRUITING, P3

Primary outcome

Number of treatment emergent adverse events (TEAEs)

Conditions studied

Diabetes Mellitus, Type 2

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.

@glp1briefing