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Sponsors › Novo Nordisk

Novo Nordisk

Every GLP‑1 and incretin trial, approval and scheduled result we hold for Novo Nordisk, drawn from ClinicalTrials.gov and Drugs@FDA.

Novo Nordisk is a commercial sponsor with 192 trials in the incretin class on file here, across 5 molecules. The programme is split between 35 early-stage trials and 157 in phase 3 or later. 30 approved FDA submissions sit against this sponsor in Drugs@FDA. The next scheduled result is 2027-03-01.

Molecules
cagrilintide · exenatide · liraglutide · semaglutide · tirzepatide
Trials on file
192
Active trials
23
Results scheduled
15
Approved FDA submissions
30

Results due

Est. completionDrugTrialPhaseParticipants
2027-03-01semaglutideA Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-termP3609
2027-05-11cagrilintideWeight Loss in People Living With Overweight or Obesity Following Treatment With CagrilintideP3300
2027-05-12cagrilintideWeight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With CagrilintideP3330
2027-05-18semaglutideA Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body WeightP3285
2027-07-12semaglutideA Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With ObesityP2230
2027-09-01semaglutideREDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood VesselsP37,101
2027-09-03semaglutideA Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 DiabetesP2270
2027-10-04semaglutideA Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 DiabetesP2300
2027-11-07semaglutideA Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 DiabetesP31,500
2028-02-22semaglutideResearch Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body WeightP3450
2028-02-23semaglutideA Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightP32,500
2028-08-28semaglutideA Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With ObesityP3400
2028-10-10semaglutideA Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to SemaglutideP3650
2028-11-15semaglutideSTEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight LossP4500
2028-12-12semaglutideAMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose WeightP31,000

FDA record

DateDrugActionApplication
2025-10-14liraglutideLabelingNDA022341
2025-05-28liraglutideLabelingNDA022341
2025-02-12liraglutideLabelingNDA022341
2024-11-01liraglutideLabelingNDA022341
2023-07-05liraglutideLabelingNDA022341
2022-06-10liraglutideLabelingNDA022341
2022-06-10liraglutideLabelingNDA022341
2020-11-20liraglutideLabelingNDA022341
2020-08-05liraglutideLabelingNDA022341
2020-01-16semaglutideType 9 - New Indication Submitted as Distinct NDA, Consolidated with Original NDA after ApprovalNDA213182
2019-06-17liraglutideEfficacyNDA022341
2017-08-25liraglutideEfficacyNDA022341
2017-07-26liraglutideREMSNDA022341
2017-04-25liraglutideLabelingNDA022341
2016-09-20liraglutideREMSNDA022341
2016-04-22liraglutideEfficacyNDA022341
2015-07-01liraglutideREMSNDA022341
2015-03-09liraglutideLabelingNDA022341
2015-02-25liraglutideLabelingNDA022341
2014-07-31liraglutideREMSNDA022341
2013-06-13liraglutideLabelingNDA022341
2013-04-16liraglutideLabelingNDA022341
2012-12-13liraglutideLabelingNDA022341
2012-12-03liraglutideManufacturing (CMC)NDA022341
2012-04-06liraglutideEfficacyNDA022341
2012-04-06liraglutideEfficacyNDA022341
2012-04-06liraglutideLabelingNDA022341
2011-05-18liraglutideLabelingNDA022341
2010-12-22liraglutideEfficacyNDA022341
2010-01-25liraglutideType 1 - New Molecular EntityNDA022341

Trials on file

All 192 incretin trials recorded for this sponsor, active first.

DrugTrialStatusPhaseParticipants
semaglutideREDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood VesselsActive, not recruitingP37,101
semaglutideA Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
NCT05567796
Active, not recruitingP33,400
semaglutideA Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightRecruitingP32,500
semaglutideA Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 DiabetesActive, not recruitingP31,500
semaglutideResearch Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
NCT04822181
Active, not recruitingP31,205
semaglutideAMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose WeightNot yet recruitingP31,000
semaglutideA Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to SemaglutideNot yet recruitingP3650
semaglutideA Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-termActive, not recruitingP3609
semaglutideSTEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight LossActive, not recruitingP4500
semaglutideA Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
NCT06717698
RecruitingP2465
semaglutideA Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
NCT07253285
RecruitingP3460
semaglutideResearch Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body WeightRecruitingP3450
semaglutideA Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With ObesityActive, not recruitingP3400
cagrilintideWeight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With CagrilintideActive, not recruitingP3330
semaglutideA Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 DiabetesRecruitingP2300
cagrilintideWeight Loss in People Living With Overweight or Obesity Following Treatment With CagrilintideActive, not recruitingP3300
semaglutideA Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body WeightNot yet recruitingP3285
semaglutideA Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 DiabetesRecruitingP2270
semaglutideA Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With ObesityRecruitingP2230
semaglutideA Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
NCT05726227
Active, not recruitingP3210
semaglutideA Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy
NCT06797869
Active, not recruitingP2142
semaglutideA Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
NCT07282613
Not yet recruitingP380
liraglutideSCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With Obesity
NCT04775082
Active, not recruitingP378
semaglutideSemaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity
NCT03574597
CompletedP317,604
semaglutideA Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes
NCT03914326
CompletedP39,651
liraglutideLiraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results
NCT01179048
CompletedP39,341
liraglutideEffect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes
NCT01272219
CompletedP33,731
semaglutideA Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease
NCT03819153
CompletedP33,533
semaglutideTrial to Evaluate Cardiovascular and Other Long-term Outcomes With Semaglutide in Subjects With Type 2 Diabetes
NCT01720446
CompletedP33,297
semaglutideA Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes
NCT02692716
CompletedP33,183
semaglutideA Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
NCT06065540
CompletedP32,734
semaglutideA Research Study to Compare Semaglutide to Insulin Aspart, When Taken Together With Metformin and Insulin Glargine, in People With Type 2 Diabetes
NCT03689374
CompletedP32,274
liraglutideEfficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes
NCT02730377
CompletedP41,991
semaglutideSTEP 1: Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
NCT03548935
CompletedP31,961
semaglutideEfficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 Diabetes
NCT02607865
CompletedP31,864
semaglutideA Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)
NCT04777396
CompletedP31,840
semaglutideA Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)
NCT04777409
CompletedP31,840
liraglutideDual Action of Liraglutide and Insulin Degludec in Type 2 Diabetes: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Subjects With Type 2 Diabetes
NCT01336023
CompletedP31,663
semaglutideResearch Study to Compare Three Doses of Semaglutide Tablets Taken Once Daily in People With Type 2 Diabetes
NCT04707469
CompletedP31,606
semaglutideA Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes
NCT04017832
CompletedP31,441
semaglutideA Research Study to See How Semaglutide Helps People With Excess Weight, Lose Weight (STEP UP)
NCT05646706
CompletedP31,407
liraglutideThe Efficacy and Safety of Liraglutide as Adjunct Therapy to Insulin in the Treatment of Type 1 Diabetes
NCT01836523
CompletedP31,398
semaglutideA Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Insulin Icodec
NCT05352815
CompletedP31,291
semaglutideLong Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial
NCT03596450
CompletedP41,278
semaglutideEfficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes
NCT01930188
CompletedP31,231
semaglutideResearch Study Investigating How Well Semaglutide Works in People With Type 2 Diabetes Suffering From Overweight or Obesity
NCT03552757
CompletedP31,210
semaglutideEfficacy and Safety of Semaglutide Versus Dulaglutide as add-on to Metformin in Subjects With Type 2 Diabetes.
NCT02648204
CompletedP31,201
semaglutideA Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose Weight
NCT05394519
CompletedP31,200
liraglutideTo Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together
NCT00318461
CompletedP31,091
semaglutideEfficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes
NCT02128932
CompletedP31,089
liraglutideEffect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
NCT00318422
CompletedP31,041
semaglutideA Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
NCT06221969
CompletedP31,024
semaglutideA Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both
NCT06534411
CompletedP31,023
semaglutideA Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE)
NCT05035082
CompletedP41,018
liraglutideA 104 Week Clinical Trial Comparing Long Term Glycaemic Control of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine Therapy in Subjects With Type 2 Diabetes Mellitus
NCT02501161
CompletedP31,012
liraglutideThe Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes
NCT00856986
CompletedP3987
semaglutideA Research Study to Compare Two Doses of Semaglutide Taken Once Weekly in People With Type 2 Diabetes
NCT03989232
CompletedP3961
semaglutideInvestigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus
NCT02453711
CompletedP2957
liraglutideEffect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes
NCT00614120
CompletedP3929
semaglutideResearch Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
NCT03548987
CompletedP3902