What happens next in GLP-1 — and when.

Get the briefing

What moved in the GLP‑1 field, in your inbox.

@glp1briefing

Trial results

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

NCT07415954 on ClinicalTrials.gov · last registry update 2026-08-10

An unusually large phase 2: 270 participants, more than double the 114 typical for the stage. Due to report 3 September 2027, alongside 39 other tracked readouts that quarter. Primary outcome, as filed: Change in glycated haemoglobin (HbA1c) (week 16). Sponsors move these dates routinely; any movement since this site started watching is listed below. semaglutide is already approved in the US for type 2 diabetes, so this is asking a further question rather than establishing the drug works at all.

Status
RECRUITING
Phase
P2
Drug
semaglutide
Rybelsus, Wegovy, Ozempic
Sponsor
Novo Nordisk A/S
Sponsor type
Industry
Enrollment
270
Started
2026-04-17
Primary completion
2027-09-03 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Change in glycated haemoglobin (HbA1c) (week 16)

Conditions studied

Diabetes Mellitus, Type 2

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.