Indications › Type 2 diabetes › liraglutide

liraglutide in type 2 diabetes

liraglutide is approved in the US for type 2 diabetes, and has 145 trials on file here in this condition. 121 of them are phase 3 or later. The next scheduled result is 2027-06.

145 registered trials study liraglutide (Saxenda, Victoza, Xultophy) in type 2 diabetes, 5 of them still active. The next is due to report 2027-12-31.

Trials on file: 145
Active: 5
Active phase 3: 0
Participants in active trials: 884
Sponsors: 80
Scheduled readouts: 1

Scheduled to report

Dates are filed by the sponsor and move often. Each links to its own record and change history.

Est. completion	Trial	Phase	Participants
2027-12-31	Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control NCT07244003 · Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.	P4	430

All trials on file

Every registered trial of liraglutide grouped under type 2 diabetes, largest first. Grouping follows the registry’s own condition wording.

Trial	Status	Phase	Sponsor
Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results NCT01179048	Completed	P3	Novo Nordisk A/S
A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes NCT01794143	Completed	P3	GRADE Study Group
Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes NCT02730377	Completed	P4	Novo Nordisk A/S
Dual Action of Liraglutide and Insulin Degludec in Type 2 Diabetes: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Subjects With Type 2 Diabetes NCT01336023	Completed	P3	Novo Nordisk A/S
To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together NCT00318461	Completed	P3	Novo Nordisk A/S
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00318422	Completed	P3	Novo Nordisk A/S
A 104 Week Clinical Trial Comparing Long Term Glycaemic Control of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine Therapy in Subjects With Type 2 Diabetes Mellitus NCT02501161	Completed	P3	Novo Nordisk A/S
The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes NCT00856986	Completed	P3	Novo Nordisk A/S
Efficacy Assessment of Insulin Glargine Versus LiraglutidE After Oral Agents Failure NCT01117350	Completed	P4	Sanofi
Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00614120	Completed	P3	Novo Nordisk A/S
Safety and Efficacy of Exenatide Once Weekly Versus Liraglutide in Subjects With Type 2 Diabetes NCT01029886	Completed	P3	AstraZeneca
A Study to Determine the Efficacy and Safety of Albiglutide as Compared With Liraglutide. NCT01128894	Completed	P3	GlaxoSmithKline
A Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes NCT03235050	Completed	P2	AstraZeneca
A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus. NCT02607306	Completed	P3	Novo Nordisk A/S
Prognostic Predictors of Response to Hypoglycemic Therapy NCT03804411	Unknown	P4	Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
To Evaluate the Effect of Liraglutide Versus Glimepiride (Amaryl®) on Haemoglobin A1c NCT00294723	Terminated	P3	Novo Nordisk A/S
A Trial Comparing Insulin Degludec/Liraglutide, Insulin Degludec, and Liraglutide in Chinese Subjects With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs (OADs) NCT03172494	Completed	P3	Novo Nordisk A/S
The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus NCT00700817	Completed	P3	Novo Nordisk A/S
Comparison of Two Treatment Regimens (Sitagliptin Versus Liraglutide) on Participants Who Failed to Achieve Good Glucose Control on Metformin Alone (MK-0431-403) NCT01296412	Completed	P3	Merck Sharp & Dohme LLC
A Trial Comparing the Efficacy and Safety of Liraglutide 1.8 mg/Day to Liraglutide 0.9 mg/Day in Japanese Subjects With Type 2 Diabetes Mellitus. NCT02505334	Completed	P3	Novo Nordisk A/S
A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes NCT01624259	Completed	P3	Eli Lilly and Company
Phase 2b Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM NCT01658501	Completed	P2	PhaseBio Pharmaceuticals Inc.
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00331851	Completed	P3	Novo Nordisk A/S
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00333151	Completed	P3	Novo Nordisk A/S
A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide Versus Insulin Glargine in Subjects With Type 2 Diabetes Mellitus NCT01952145	Completed	P3	Novo Nordisk A/S
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period NCT02787551	Completed	P3	Sanofi
A Trial Investigating the Efficacy and Safety of Insulin Degludec/Liraglutide Injection in Subjects With Type 2 Diabetes NCT06559722	Unknown	P3	Tonghua Dongbao Pharmaceutical Co.,Ltd
A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus NCT02420262	Completed	P3	Novo Nordisk A/S
A Monotherapy Study to Evaluate the Efficacy and Safety of 2 Dose Levels of Albiglutide in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM) NCT01733758	Completed	P3	GlaxoSmithKline
A Study of LY2189265 in Japanese Participants With Type 2 Diabetes Mellitus NCT01558271	Completed	P3	Eli Lilly and Company
Effect of Liraglutide or Exenatide Added to an Ongoing Treatment on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00518882	Completed	P3	Novo Nordisk A/S
A Trial Comparing Insulin Degludec/Liraglutide and Insulin Degludec in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Therapy and Metformin With or Without One Other Oral Antidiabetic Drug (OAD) NCT03175120	Completed	P3	Novo Nordisk A/S
The Effect of Liraglutide Versus Placebo When Added to Basal Insulin Analogues With or Without Metformin in Subjects With Type 2 Diabetes NCT01617434	Completed	P3	Novo Nordisk A/S
The Efficacy of Insulin Degludec/Liraglutide in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on GLP-1 Receptor Agonist and OAD Therapy NCT01676116	Completed	P3	Novo Nordisk A/S
The Efficacy of Insulin Degludec/Liraglutide as add-on Therapy in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on Sulphonylurea With or Without Metformin Therapy NCT01618162	Completed	P3	Novo Nordisk A/S
Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control NCT07244003	Recruiting	P4	Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Study to Assess the Efficacy and Safety of Liraglutide in the Treatment of Type 2 Diabetes NCT04373967	Unknown	P3	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration Algorithms NCT02298192	Completed	P3	Novo Nordisk A/S
A Clinical Trial Comparing Glycaemic Control and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine (IGlar) as add-on Therapy to SGLT2i in Subjects With Type 2 Diabetes Mellitus NCT02773368	Completed	P3	Novo Nordisk A/S
Comparison of the Efficacy and Safety of Two Intensification Strategies in Subjects With Type 2 Diabetes Inadequately Controlled on Basal Insulin and Metformin NCT01388361	Completed	P3	Novo Nordisk A/S
A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec in Subjects With Type 2 Diabetes NCT01392573	Completed	P3	Novo Nordisk A/S
Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin NCT01907854	Completed	P4	Novo Nordisk A/S
Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 Diabetes NCT01973231	Completed	P4	Novo Nordisk A/S
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00393718	Completed	P3	Novo Nordisk A/S
The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes NCT02008682	Completed	P4	Novo Nordisk A/S
Safety and Efficacy of Liraglutide in Combination With an OAD in Subjects With Type 2 Diabetes Insufficiently Controlled on OAD Alone NCT01512108	Completed	P3	Novo Nordisk A/S
The Effect of Insulin Degludec in Combination With Liraglutide and Metformin in Subjects With Type 2 Diabetes Qualifying for Treatment Intensification NCT01664247	Completed	P3	Novo Nordisk A/S
Efficacy and Safety of Liraglutide Versus Sulphonylurea Both in Combination With Metformin During Ramadan in Subjects With Type 2 Diabetes NCT01917656	Completed	P4	Novo Nordisk A/S
LIRA-ADD2SGLT2i - Liraglutide Versus Placebo as add-on to SGLT2 Inhibitors. NCT02964247	Completed	P3	Novo Nordisk A/S
Comparing Efficacy and Safety of CinnaGen-liraglutide Versus Victoza® in Patients With Type II Diabetes NCT03421119	Unknown	P3	Cinnagen
A Study to Assess the Safety and Efficacy of SAR425899 in Patients With Type 2 Diabetes Mellitus NCT02973321	Completed	P2	Sanofi
Efficacy and Safety of Liraglutide Versus Placebo as add-on to Existing Diabetes Medication in Subjects With Type 2 Diabetes and Moderate Renal Impairment NCT01620489	Completed	P3	Novo Nordisk A/S
Liraglutide Hospital Discharge Trial NCT01919489	Completed	P4	Emory University
RISE Adult Medication Study NCT01779362	Completed	P3	RISE Study Group
Effect of Liraglutide in Combination With Sulfonylurea (SU) on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00395746	Completed	P3	Novo Nordisk A/S
Durability of Combination of Insulin and GLP-1 Receptor Agonist or SGLT-2 Inhibitors Versus Basal Bolus Insulin Regimen in Type 2 Diabetes (BEYOND) NCT04196231	Completed	P4	University of Campania Luigi Vanvitelli
Efficacy and Safety of Liraglutide in Combination With Insulin Therapy Compared to Insulin Alone in Japanese Subjects With Type 2 Diabetes NCT01572740	Completed	P3	Novo Nordisk A/S
The Efficacy and Safety of Insulin Degludec/Liraglutide Combination (IDegLira) in Patients With Type 2 Diabetes NCT06408532	Unknown	P4	Peking University People's Hospital
Glycaemic Control of Weekly LAPS-Exendin Versus Placebo in Subjects of Type 2 Diabetes NCT02057172	Completed	P2	Hanmi Pharmaceutical Company Limited
Effect of Liraglutide on Blood Glucose Control in Japanese Subjects With Type 2 Diabetes NCT00154414	Completed	P2	Novo Nordisk A/S

See the full record for liraglutide, or every molecule being studied in type 2 diabetes. These are registered trials, nothing more. Most drugs tested in a new condition never get approved for it, and plenty of these will report nothing useful.