What happens next in GLP-1 — and when.

Sponsors › The Cleveland Clinic

The Cleveland Clinic

Every GLP‑1 and incretin trial, approval and scheduled result we hold for The Cleveland Clinic, drawn from ClinicalTrials.gov and Drugs@FDA.

The Cleveland Clinic is an academic or hospital sponsor, not a drug company with 8 trials in the incretin class on file here, across 3 molecules. The programme is split between 2 early-stage trials and 6 in phase 3 or later. The next scheduled result is 2026-12-31.

Molecules
liraglutide · semaglutide · tirzepatide
Trials on file
8
Active trials
5
Results scheduled
2
Approved FDA submissions
0

Results due

Est. completionDrugTrialPhaseParticipants
2026-12-31tirzepatideTIRzepatide for the Treatment of Obesity in Patients With Atrial FibrillationP2100
2027-04-28semaglutideSequential Therapy Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)P4150

Trials on file

All 8 incretin trials recorded for this sponsor, active first.

DrugTrialStatusPhaseParticipants
semaglutideSequential Therapy Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)Active, not recruitingP4150
semaglutideFibrosis Lessens After Metabolic SurgeryRecruitingP4120
tirzepatideTIRzepatide for the Treatment of Obesity in Patients With Atrial FibrillationRecruitingP2100
semaglutideOptimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver DiseaseRecruitingP470
tirzepatideGLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPDNot yet recruitingP230
liraglutideEMI-EHP Weight Management and Type 2 Diabetes Pragmatic TrialTerminatedP474
semaglutideHolding vs. Continuing Incretin-based Therapies Before Upper EndoscopyCompletedP469
semaglutideTransition From Basal/Bolus to Once-weekly Subcutaneous Semaglutide and Basal Insulin in Patients With T2DCompletedP460
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