What happens next in GLP-1 — and when.

Sponsors › Mayo Clinic

Mayo Clinic

Every GLP‑1 and incretin trial, approval and scheduled result we hold for Mayo Clinic, drawn from ClinicalTrials.gov and Drugs@FDA.

Mayo Clinic is an academic or hospital sponsor, not a drug company with 14 trials in the incretin class on file here, across 4 molecules. The programme is split between 3 early-stage trials and 11 in phase 3 or later. The next scheduled result is 2026-12-31.

Molecules
exenatide · liraglutide · semaglutide · tirzepatide
Trials on file
14
Active trials
7
Results scheduled
2
Approved FDA submissions
0

Results due

Est. completionDrugTrialPhaseParticipants
2027-12semaglutideA Study of a Novel Precision Medicine Approach For ObesityP4135
2028-02-01semaglutideIndividualized Pharmacological Approach to Obesity in Patients With Bipolar DisorderP4100

Trials on file

All 14 incretin trials recorded for this sponsor, active first.

DrugTrialStatusPhaseParticipants
semaglutideA Study of a Novel Precision Medicine Approach For ObesityActive, not recruitingP4135
semaglutideIndividualized Pharmacological Approach to Obesity in Patients With Bipolar DisorderRecruitingP4100
liraglutideThe Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 DiabetesRecruitingP260
semaglutideSemaglutide and Structured Lifestyle Support to Improve Heart and Blood Vessel Health in Postmenopausal Obese Breast Cancer Survivors Taking Aromatase InhibitorsNot yet recruitingP450
tirzepatideThe Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With ObesityRecruitingP440
semaglutideAging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal WomenEnrolling by invitationP430
semaglutideEffects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor FunctionsActive, not recruitingP430
liraglutideIndividualized Obesity PharmacotherapyCompletedP3193
semaglutideCardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection FractionCompletedP481
liraglutideEffect of GLP-1 Receptor Agonism After Sleeve GastrectomyCompletedP346
liraglutidePilot Study of the Effect of Liraglutide on Weight Loss and Gastric Functions in ObesityCompletedP240
exenatideEffect of Exenatide in Obese Patients With Accelerated Gastric EmptyingCompletedP420
exenatideAssess the Efficacy and Safety of Exenatide SR for the Prevention of Diabetes After Kidney TransplantationCompletedP29
exenatideExenatide on GI Motor Function and Permeability in Short Bowel SyndromeWithdrawnP4—
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