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Sponsors › Amgen

Amgen

Every GLP‑1 and incretin trial, approval and scheduled result we hold for Amgen, drawn from ClinicalTrials.gov and Drugs@FDA.

Amgen is a commercial sponsor with 13 trials in the incretin class on file here, all of maridebart cafraglutide. The programme is split between 3 early-stage trials and 10 in phase 3 or later. No approved FDA submission is recorded against this sponsor for these molecules, which is normal for a programme that has not reached the market. The next scheduled result is 2027-01-21.

Molecules
maridebart cafraglutide
Trials on file
13
Active trials
12
Results scheduled
11
Approved FDA submissions
0

Results due

Est. completionDrugTrialPhaseParticipants
2027-01-21maridebart cafraglutideEfficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are OverweightP31,105
2027-01-21maridebart cafraglutideEvaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are OverweightP33,853
2027-04-27maridebart cafraglutideEfficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity DiseaseP3279
2027-09-29maridebart cafraglutideA Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or OverweightP2180
2027-09-29maridebart cafraglutideMaridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) TherapyP3250
2027-09-29maridebart cafraglutideMaridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure TherapyP3250
2027-12-26maridebart cafraglutideExtension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)P33,200
2027-12-26maridebart cafraglutideExtension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)P3950
2028-01-03maridebart cafraglutideEfficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)P3300
2028-06-30maridebart cafraglutideEvaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or ObesityP312,800
2028-06-30maridebart cafraglutideMaridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and ObesityP35,056

Trials on file

All 13 incretin trials recorded for this sponsor, active first.

DrugTrialStatusPhaseParticipants
maridebart cafraglutideEvaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or ObesityRecruitingP312,800
maridebart cafraglutideMaridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and ObesityRecruitingP35,056
maridebart cafraglutideEvaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are OverweightActive, not recruitingP33,853
maridebart cafraglutideExtension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)RecruitingP33,200
maridebart cafraglutideEfficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are OverweightActive, not recruitingP31,105
maridebart cafraglutideExtension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)RecruitingP3950
maridebart cafraglutideA Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)
NCT06660173
Active, not recruitingP2409
maridebart cafraglutideEfficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)RecruitingP3300
maridebart cafraglutideEfficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity DiseaseActive, not recruitingP3279
maridebart cafraglutideMaridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) TherapyRecruitingP3250
maridebart cafraglutideMaridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure TherapyRecruitingP3250
maridebart cafraglutideA Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or OverweightRecruitingP2180
maridebart cafraglutideDose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus
NCT05669599
CompletedP2592