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Trial results

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

NCT07684235 on ClinicalTrials.gov · last registry update 2026-09-03

An unusually large phase 3: 3,200 participants, more than double the 424 typical for the stage. Due to report 26 December 2027, alongside 38 other tracked readouts that quarter. Primary outcome, as filed: Percent Change in Body Weight from Baseline of the Parent Trial (20210181). Sponsors move these dates routinely; any movement since this site started watching is listed below. maridebart cafraglutide is not approved in the US for anything yet, so this is a drug in development rather than an established treatment being extended.

Status
RECRUITING
Phase
P3
Drug
maridebart cafraglutide
Sponsor
Amgen
Sponsor type
Industry
Enrollment
3,200
Started
2026-07-23
Primary completion
2027-12-26 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Percent Change in Body Weight from Baseline of the Parent Trial (20210181)

Conditions studied

Obesity · Overweight

Every field above is taken directly from the registry record. See all detected changes across the class, or the maridebart cafraglutide page for this molecule’s full trial and approval history.