| semaglutide | New Triple Therapy in Newly Diagnosed Type 2 Diabetes | Not yet recruiting | P3 | 296 |
| tirzepatide | New Triple Combination Therapy in Newly Diagnosed Type 2 Diabetes NCT07635953 · Sun Yat-sen University | Not yet recruiting | P3 | 296 |
| semaglutide | Impact GLP-1 Agonists Following Bariatric | Recruiting | P4 | 150 |
| semaglutide | Assessing Incretin Therapy for Cardiovascular Risk Reduction and Diabetes Remission( ITCRDR Study) | Enrolling by invitation | P4 | 142 |
| semaglutide | Semaglutide Treatment in Type 1 Diabetes | Not yet recruiting | P3 | 122 |
| semaglutide | Semaglutide Treatment for Hyperglycaemia After Renal Transplantation | Recruiting | P4 | 104 |
| tirzepatide | Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide | Recruiting | P4 | 104 |
| semaglutide | Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis | Recruiting | P4 | 100 |
| lixisenatide | Evaluation of the Efficacy and Safety of GLP-1 Receptor Agonist Therapy In Steroid-Induced Diabetes | Enrolling by invitation | P4 | 100 |
| semaglutide | Semaglutide 2.4 mg in Patients With Poor Weight-loss NCT05073835 · University College, London | Active, not recruiting | P3 | 70 |
| tirzepatide | Tirzepatide's Effects on Epigenetic Aging and Metabolic Restoration in Virally Suppressed People With HIV NCT07707778 · National Taiwan University Clinical Trial Center | Enrolling by invitation | P4 | 60 |
| semaglutide | Semaglutide vs Sitagliptin NCT05195944 · University Health Network, Toronto | Enrolling by invitation | P4 | 58 |
| dulaglutide | GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance NCT04731272 · University of Pennsylvania | Recruiting | P2 | 30 |
| semaglutide | Alleviating Carbohydrate Counting for Patients with Type-1 Diabetes Using a Closed Loop System with Weekly Subcutaneous Semaglutide NCT06387199 · McGill University Health Centre/Research Institute of the McGill University Health Centre | Recruiting | P2/P3 | 26 |
| albiglutide | Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus | Completed | P4 | 9,463 |
| liraglutide | Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results NCT01179048 · Novo Nordisk A/S | Completed | P3 | 9,341 |
| semaglutide | Trial to Evaluate Cardiovascular and Other Long-term Outcomes With Semaglutide in Subjects With Type 2 Diabetes NCT01720446 · Novo Nordisk A/S | Completed | P3 | 3,297 |
| semaglutide | A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes NCT02692716 · Novo Nordisk A/S | Completed | P3 | 3,183 |
| liraglutide | Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes NCT02730377 · Novo Nordisk A/S | Completed | P4 | 1,991 |
| semaglutide | Efficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 Diabetes NCT02607865 · Novo Nordisk A/S | Completed | P3 | 1,864 |
| liraglutide | Dual Action of Liraglutide and Insulin Degludec in Type 2 Diabetes: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Subjects With Type 2 Diabetes NCT01336023 · Novo Nordisk A/S | Completed | P3 | 1,663 |
| liraglutide | The Efficacy and Safety of Liraglutide as Adjunct Therapy to Insulin in the Treatment of Type 1 Diabetes NCT01836523 · Novo Nordisk A/S | Completed | P3 | 1,398 |
| semaglutide | Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes NCT01930188 · Novo Nordisk A/S | Completed | P3 | 1,231 |
| semaglutide | Efficacy and Safety of Semaglutide Versus Dulaglutide as add-on to Metformin in Subjects With Type 2 Diabetes. NCT02648204 · Novo Nordisk A/S | Completed | P3 | 1,201 |
| liraglutide | To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together NCT00318461 · Novo Nordisk A/S | Completed | P3 | 1,091 |
| semaglutide | Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes NCT02128932 · Novo Nordisk A/S | Completed | P3 | 1,089 |
| liraglutide | Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00318422 · Novo Nordisk A/S | Completed | P3 | 1,041 |
| liraglutide | A 104 Week Clinical Trial Comparing Long Term Glycaemic Control of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine Therapy in Subjects With Type 2 Diabetes Mellitus NCT02501161 · Novo Nordisk A/S | Completed | P3 | 1,012 |
| liraglutide | The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes NCT00856986 · Novo Nordisk A/S | Completed | P3 | 987 |
| liraglutide | Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00614120 · Novo Nordisk A/S | Completed | P3 | 929 |
| semaglutide | Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People With Obesity NCT05579977 · Pfizer | Terminated | P2 | 902 |
| semaglutide | Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT) NCT03061214 · Novo Nordisk A/S | Completed | P3 | 868 |
| liraglutide | The Efficacy and Safety of Liraglutide Adjunct to Insulin Treatment in Type 1 Diabetes NCT02098395 · Novo Nordisk A/S | Completed | P3 | 835 |
| semaglutide | Efficacy and Safety of Oral Semaglutide Versus Empagliflozin in Subjects With Type 2 Diabetes Mellitus NCT02863328 · Novo Nordisk A/S | Completed | P3 | 822 |
| liraglutide | A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus. NCT02607306 · Novo Nordisk A/S | Completed | P3 | 819 |
| semaglutide | Efficacy and Safety of Semaglutide Once-weekly Versus Exenatide ER 2.0 mg Once-weekly as add-on to 1-2 Oral Antidiabetic Drugs (OADs) in Subjects With Type 2 Diabetes NCT01885208 · Novo Nordisk A/S | Completed | P3 | 813 |
| semaglutide | Efficacy and Safety of Semaglutide Versus Canagliflozin as add-on to Metformin in Subjects With Type 2 Diabetes NCT03136484 · Novo Nordisk A/S | Completed | P3 | 788 |
| liraglutide | To Evaluate the Effect of Liraglutide Versus Glimepiride (Amaryl®) on Haemoglobin A1c NCT00294723 · Novo Nordisk A/S | Terminated | P3 | 746 |
| semaglutide | Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Insulin NCT03021187 · Novo Nordisk A/S | Completed | P3 | 731 |
| liraglutide | A Trial Comparing Insulin Degludec/Liraglutide, Insulin Degludec, and Liraglutide in Chinese Subjects With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs (OADs) NCT03172494 · Novo Nordisk A/S | Completed | P3 | 720 |
| semaglutide | Efficacy and Safety of Oral Semaglutide Versus Liraglutide and Versus Placebo in Subjects With Type 2 Diabetes Mellitus NCT02863419 · Novo Nordisk A/S | Completed | P3 | 711 |
| semaglutide | Dose-finding of Semaglutide Administered Subcutaneously Once Daily Versus Placebo and Liraglutide in Subjects With Type 2 Diabetes NCT02461589 · Novo Nordisk A/S | Completed | P2 | 706 |
| semaglutide | Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Diet and Exercise Only NCT02906930 · Novo Nordisk A/S | Completed | P3 | 703 |
| exenatide | Phase 3 28-Week Study With 24-Week and 52-week Extension Phases to Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo NCT02229396 · AstraZeneca | Completed | P3 | 695 |
| liraglutide | The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus NCT00700817 · Novo Nordisk A/S | Completed | P3 | 665 |
| liraglutide | A Trial Comparing the Efficacy and Safety of Liraglutide 1.8 mg/Day to Liraglutide 0.9 mg/Day in Japanese Subjects With Type 2 Diabetes Mellitus. NCT02505334 · Novo Nordisk A/S | Completed | P3 | 635 |
| semaglutide | Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 Diabetes NCT01923181 · Novo Nordisk A/S | Completed | P2 | 632 |
| semaglutide | A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly in Monotherapy or in Combination With One OAD in Japanese Subjects With Type 2 Diabetes NCT02207374 · Novo Nordisk A/S | Completed | P3 | 601 |
| dulaglutide | A Study of Two Doses of Dulaglutide (LY2189265) in Japanese Patients With Type 2 Diabetes NCT04809220 · Eli Lilly and Company | Completed | P3 | 591 |
| liraglutide | Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00331851 · Novo Nordisk A/S | Completed | P3 | 584 |
| semaglutide | Research Study Comparing a New Medicine Semaglutide to Liraglutide in People With Type 2 Diabetes NCT03191396 · Novo Nordisk A/S | Completed | P3 | 577 |
| liraglutide | Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00333151 · Novo Nordisk A/S | Completed | P3 | 576 |
| liraglutide | A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide Versus Insulin Glargine in Subjects With Type 2 Diabetes Mellitus NCT01952145 · Novo Nordisk A/S | Completed | P3 | 557 |
| liraglutide | A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus NCT02420262 · Novo Nordisk A/S | Completed | P3 | 506 |
| semaglutide | Efficacy and Safety of Oral Semaglutide Using a Flexible Dose Adjustment Based on Clinical Evaluation Versus Sitagliptin in Subjects With Type 2 Diabetes Mellitus. NCT02849080 · Novo Nordisk A/S | Completed | P3 | 504 |
| liraglutide | Effect of Liraglutide or Exenatide Added to an Ongoing Treatment on Blood Glucose Control in Subjects With Type 2 Diabetes NCT00518882 · Novo Nordisk A/S | Completed | P3 | 467 |
| exenatide | Phase III Study to Evaluate Safety and Efficacy of Added Exenatide Versus Placebo to Titrated Basal Insulin Glargine in Inadequately Controlled Patients With Type II Diabetes Mellitus NCT02229383 · AstraZeneca | Completed | P3 | 464 |
| semaglutide | Safety and Efficacy of Oral Semaglutide Versus Dulaglutide Both in Combination With One OAD (Oral Antidiabetic Drug) in Japanese Subjects With Type 2 Diabetes NCT03015220 · Novo Nordisk A/S | Completed | P3 | 458 |
| liraglutide | A Trial Comparing Insulin Degludec/Liraglutide and Insulin Degludec in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Therapy and Metformin With or Without One Other Oral Antidiabetic Drug (OAD) NCT03175120 · Novo Nordisk A/S | Completed | P3 | 453 |
| liraglutide | The Effect of Liraglutide Versus Placebo When Added to Basal Insulin Analogues With or Without Metformin in Subjects With Type 2 Diabetes NCT01617434 · Novo Nordisk A/S | Completed | P3 | 451 |