What happens next in GLP-1 — and when.

Trial results

Focusing on the Menopausal Transition to Improve Mid-Life Women's Health

NCT06975111 on ClinicalTrials.gov · last registry update 2026-07-21

An unusually large phase 2/phase 3: 200 participants, more than double the 60 typical for the stage. Due to report 31 October 2029, alongside 7 other tracked readouts that quarter. Primary outcome, as filed: Epigenetic aging measurements of "PhenoAge". Sponsors move these dates routinely; any movement since this site started watching is listed below. semaglutide is already approved in the US for cardiovascular disease, so this is asking a further question rather than establishing the drug works at all.

Status
RECRUITING
Phase
P2/P3
Drug
semaglutide
Ozempic, Rybelsus, Wegovy
Sponsor
University of Colorado, Denver
Sponsor type
Other
Enrollment
200
Started
2026-03-01
Primary completion
2029-10-31 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Epigenetic aging measurements of "PhenoAge"

Conditions studied

Menopause · Menopause Hot Flashes · Menopause Related Conditions · Cardiovascular

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.

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