What happens next in GLP-1 — and when.

Trial results

PEG-rhGH and Semaglutide Combination Therapy in Non-Diabetic Obese Adults

NCT06863363 on ClinicalTrials.gov · last registry update 2025-03-07

An unusually large phase 4: 212 participants, more than double the 75 typical for the stage. Primary outcome, as filed: The change in lean body weight (kg) from baseline. semaglutide is already approved in the US for obesity, so this is asking a further question rather than establishing the drug works at all.

Status
NOT_YET_RECRUITING
Phase
P4
Drug
semaglutide
Ozempic, Rybelsus, Wegovy
Sponsor
Shanghai Zhongshan Hospital
Sponsor type
Other
Enrollment
212

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

The change in lean body weight (kg) from baseline

Conditions studied

Non-diabetic Obesity

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.

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