What happens next in GLP-1 — and when.

Get the briefing

What moved in the GLP‑1 field, in your inbox.

@glp1briefing

Trial results

A Study Investigating Oral Semaglutide in People with Open-Angle Glaucoma

NCT06792422 on ClinicalTrials.gov · last registry update 2025-01-24

Recruiting now, toward 126 participants. Due to report August 2028, alongside 21 other tracked readouts that quarter. Primary outcome, as filed: Photopic negative response of the electroretinogram after 6 months. Sponsors move these dates routinely; any movement since this site started watching is listed below.

Status
RECRUITING
Phase
P4
Drug
semaglutide
Rybelsus, Wegovy, Ozempic
Sponsor
Glostrup University Hospital, Copenhagen
Sponsor type
Other
Enrollment
126
Started
2025-01
Primary completion
2028-08 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Photopic negative response of the electroretinogram after 6 months

Conditions studied

Primary Open Angle Glaucoma (POAG) · Open-Angle Glaucoma · Glaucoma

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.