What happens next in GLP-1 — and when.

Trial results

A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities

NCT05822830 on ClinicalTrials.gov · last registry update 2025-11-26

Finished 13 November 2024, after enrolling 751 people. Primary outcome, as filed: Percent Change From Baseline in Body Weight. semaglutide is already approved in the US for obesity, so this is asking a further question rather than establishing the drug works at all.

Status
COMPLETED
Phase
P3
Drug
semaglutide
Ozempic, Rybelsus, Wegovy
Sponsor
Eli Lilly and Company
Sponsor type
Industry
Enrollment
751
Started
2023-04-21
Primary completion
2024-11-13 actual

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Percent Change From Baseline in Body Weight

Conditions studied

Obesity · Overweight

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.

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