What happens next in GLP-1 — and when.

Get the briefing

What moved in the GLP‑1 field, in your inbox.

@glp1briefing

IndicationsObesity & overweight › mazdutide

mazdutide in obesity & overweight

mazdutide is not approved in the US for obesity & overweight, and has 10 trials on file here in this condition. 6 of them are phase 3 or later. The next scheduled result is 2026-09-24. Being studied in a condition is not the same as being approved for it; most such programmes end without an approval.

10 registered trials study mazdutide in obesity & overweight, 6 of them still active and 3 in phase 3. The next is due to report 2026-09-24.

Trials on file
10
Active
6
Active phase 3
3
Participants in active trials
1,161
Sponsors
4
Scheduled readouts
4

Scheduled to report

Dates are filed by the sponsor and move often. Each links to its own record and change history.

Est. completionTrialPhaseParticipants
2026-09-24A Study of IBI362 in Subjects With HFpEF or HFmrEF Combined With Obesity
NCT06862908 · Innovent Biologics (Suzhou) Co. Ltd.
P2141
2027-05-07A Study of IBI362 in Chinese Subjects With Obstructive Sleep Apnea and BMI≥28 kg/m2
NCT06931028 · Innovent Biologics (Suzhou) Co. Ltd.
P3260
2027-10-31A Study of IBI362 in Chinese Adolescents With Obesity or Overweight
NCT07255209 · Innovent Biologics (Suzhou) Co. Ltd.
P3180
2027-12-31Effect of Mazdutide on Coronary Plaque in Patients With Coronary Atherosclerosis and Overweight or Obesity
NCT07657676 · China National Center for Cardiovascular Diseases
P4116

All trials on file

Every registered trial of mazdutide grouped under obesity & overweight, largest first. Grouping follows the registry’s own condition wording.

TrialStatusPhaseSponsor
A Study of IBI362 in Participants With Obesity or Overweight
NCT05607680
CompletedP3Innovent Biologics (Suzhou) Co. Ltd.
A Study of IBI362 9 mg in Chinese Adults With ObesityUnknownP3Innovent Biologics (Suzhou) Co. Ltd.
Efficacy and Safety of IBI362 in Hypertensive Patients With Overweight/Obesity
NCT07469800
RecruitingP3Innovent Biologics (Suzhou) Co. Ltd.
A Study of IBI362 Evaluating Weight Loss in Obese and Overweight Chinese Subjects
NCT04904913
CompletedP2Innovent Biologics (Suzhou) Co. Ltd.
A Study of IBI362 in Chinese Subjects With Obstructive Sleep Apnea and BMI≥28 kg/m2RecruitingP3Innovent Biologics (Suzhou) Co. Ltd.
A Study of IBI362 in Chinese Adolescents With Obesity or OverweightRecruitingP3Innovent Biologics (Suzhou) Co. Ltd.
A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight
NCT06124807
CompletedP2Eli Lilly and Company
A Study of IBI362 in Subjects With HFpEF or HFmrEF Combined With ObesityRecruitingP2Innovent Biologics (Suzhou) Co. Ltd.
Mazdutide Plus LNG-IUS for Fertility-Sparing Treatment of AEH or Early Endometrial CancerNot yet recruitingP2Tongji Hospital
Effect of Mazdutide on Coronary Plaque in Patients With Coronary Atherosclerosis and Overweight or ObesityNot yet recruitingP4China National Center for Cardiovascular Diseases

See the full record for mazdutide, or every molecule being studied in obesity & overweight. These are registered trials, nothing more. Most drugs tested in a new condition never get approved for it, and plenty of these will report nothing useful.