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IndicationsType 2 diabetes › lixisenatide

lixisenatide in type 2 diabetes

lixisenatide is approved in the US for type 2 diabetes, and has 44 trials on file here in this condition. 42 of them are phase 3 or later. The next scheduled result is 2026-09-18.

44 registered trials study lixisenatide (Soliqua, Adlyxin) in type 2 diabetes, 3 of them still active. The next is due to report 2026-09-18.

Trials on file
44
Active
3
Active phase 3
0
Participants in active trials
2,318
Sponsors
10
Scheduled readouts
3

Scheduled to report

Dates are filed by the sponsor and move often. Each links to its own record and change history.

Est. completionTrialPhaseParticipants
2026-09-18iGlarLixi CGM Study in Chinese T2D Individuals After OADs
NCT06671587 · Sanofi
P4678
2027-06-30Regimen Transition After Short-Term Intensive Insulin Therapy in Type 2 Diabetes
NCT07173712 · Yanbing Li
P4324
2027-06-30Efficacy and Safety of iGlarLixi Versus Standard of Care in a Real-world Adult China Population With Uncontrolled Type 2 Diabetes on Oral Agents
NCT07307235 · Shanghai Zhongshan Hospital
P41,316

All trials on file

Every registered trial of lixisenatide grouped under type 2 diabetes, largest first. Grouping follows the registry’s own condition wording.

TrialStatusPhaseSponsor
Efficacy and Safety of iGlarLixi Versus Standard of Care in a Real-world Adult China Population With Uncontrolled Type 2 Diabetes on Oral AgentsRecruitingP4Shanghai Zhongshan Hospital
Efficacy and Safety of Insulin Glargine/ Lixisenatide Fixed Ratio Combination Compared to Insulin Glargine Alone and Lixisenatide Alone on Top of Metformin in Patients With T2DMCompletedP3Sanofi
Efficacy and Safety of Lixisenatide Versus Insulin Glulisine on Top of Insulin Glargine With or Without Metformin in Type 2 Diabetic PatientsCompletedP3Sanofi
Evaluation of Insulin Glargine/Lixisenatide Fixed Ratio Combination in Patients With Type 2 Diabetes Insufficiently Controlled With Oral Antidiabetic Drug(s)CompletedP3Sanofi
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of SulfonylureaCompletedP3Sanofi
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 DiabetesCompletedP3Sanofi
GLP-1 Receptor Agonist Lixisenatide (Morning or Evening) in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of MetforminCompletedP3Sanofi
iGlarLixi CGM Study in Chinese T2D Individuals After OADsRecruitingP4Sanofi
iGlarLixi vs IDegAsp in Chinese Participants After OAD(s)CompletedP3Sanofi
Dose Ranging Study of the GLP-1 Agonist AVE0010 in Metformin-Treated Subjects With Type 2 Diabetes MellitusCompletedP2Sanofi
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (LixiLan) to Insulin Glargine Alone on Top of Oral Anti-diabetic Drugs (OADs) With Type 2 Diabetes in JapanCompletedP3Sanofi
Efficacy and Safety of LixiLan Versus Insulin Glargine Alone Both With Metformin in Japanese With Type 2 Diabetes Mellitus Inadequately Controlled on Basal Insulin and Oral Antidiabetic DrugsCompletedP3Sanofi
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Basal InsulinCompletedP3Sanofi
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of PioglitazoneCompletedP3Sanofi
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of MetforminCompletedP3Sanofi
Comparison of Lixisenatide Injected Prior to the Main Meal of the Day Versus Prior to Breakfast in Type 2 Diabetic Patients on MetforminCompletedP3Sanofi
Assessment of the Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Insufficiently Controlled With Basal Insulin +/- MetforminCompletedP3Sanofi
24-week Treatment With Lixisenatide in Type 2 Diabetes Insufficiently Controlled With Metformin and Insulin GlargineCompletedP3Sanofi
Comparison of the Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Ratio Combination to Insulin Glargine in Patients With Type 2 Diabetes Insufficiently Controlled on Basal InsulinCompletedP3Sanofi
Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled by MetforminCompletedP3Sanofi
Safety And Tolerability Of Lixisenatide In Monotherapy In Patients With Type 2 DiabetesCompletedP3Sanofi
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation in MonotherapyCompletedP3Sanofi
Efficacy and Safety of Lixisenatide Versus Placebo on Top of Basal Insulin and/or Oral Antidiabetic Treatment in Older Type 2 Diabetic PatientsCompletedP3Sanofi
Regimen Transition After Short-Term Intensive Insulin Therapy in Type 2 DiabetesNot yet recruitingP4Yanbing Li
Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Combination Versus Insulin Glargine Alone on Top of Metformin in Type 2 Diabetic PatientsCompletedP2Sanofi
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (LixiLan) to Lixisenatide on Top of Oral Anti-diabetic Drugs (OADs) With Type 2 Diabetes in JapanCompletedP3Sanofi
24-week Study Comparing Lixisenatide to Sitagliptin as add-on to Metformin in Obese Type 2 Diabetic Patients Younger Than 50 YearsCompletedP3Sanofi
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Basal Insulin +/- Sulfonylurea (GETGOAL-L-ASIA)CompletedP3Sanofi
Safety and Tolerability of Lixisenatide in Combination With Oral Anti-Diabetic Treatment in Patients With Type 2 DiabetesCompletedP3Sanofi
Study Comparing the Efficacy and Safety of Insulin Glargine (Basal Insulin)/Lixisenatide (GLP-1 Receptor Agonist) Combination (Soliqua™) in Patients With Type 2 Diabetes Mellitus (T2DM)CompletedP3Sanofi
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes (LixiLan-India)CompletedP3Sanofi
Efficacy and Safety of Soliqua Versus Lantus in Ethnically/Racially Diverse Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Basal Insulin and Oral Antidiabetic AgentsTerminatedP3Sanofi
Safety Assessment of Lyxumia (Lixisenatide) and Sulfonylurea as Add-on Treatment to Basal Insulin in Uncontrolled Patients With Type 2 Diabetes Mellitus Who Elect to Fast During RamadanCompletedP4Sanofi
Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IGlarLixiCompletedP3Population Health Research Institute
Effect of Lixisenatide on Postprandial Plasma Glucose Compared to Sitagliptin in Combination With Insulin GlargineCompletedP4Sanofi
Effect of Soliqua 100/33 on Time in Range From Continuous Glucose Monitoring in Insulin-naive Patients With Very Uncontrolled Type 2 Diabetes MellitusCompletedP4Sanofi
The Effect of Soliqua on Glucose Variability in Type 2 Patients Among South AsiansCompletedP4LMC Diabetes & Endocrinology Ltd.
A Study to Investigate Safety and Efficacy of iGlarLixi in Adult Patients With Type 2 Diabetes MellitusCompletedP4Sanofi
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation in Monotherapy (GETGOAL-MONO Japan LTS)CompletedP3Sanofi
Study on Lixisenatide and Counterregulation to HypoglycemiaCompletedP4Lund University
Feasibility of Once/Daily Administered GLP/1 Receptoragonist (Lixisenatide) in Combination With Basal InsulinCompletedP3Medical University of Vienna
Lixisenatide-The Effects on Glucose and Lipid Metabolism in Type 2 DiabetesCompletedP4University of Surrey
Evaluation of Lixisenatide Efficacy in Diabetes Mellitus Type 2 With Failure of Other GLP-1 AnalogTerminatedP4Laniado Hospital
Effects of Insulin Glargine and Lixisenatide on the BrainTerminatedP4University Hospital Tuebingen

See the full record for lixisenatide, or every molecule being studied in type 2 diabetes. These are registered trials, nothing more. Most drugs tested in a new condition never get approved for it, and plenty of these will report nothing useful.