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Pipelineliraglutide › Saxenda

Saxenda

Saxenda is a brand of liraglutide from Novo Nordisk, first approved by the FDA on 2014-12-23 under application NDA206321, authorised in the EU as Saxenda, currently listed in shortage by the FDA (1 record).

Saxenda is Novo Nordisk's brand of liraglutide, approved under NDA206321. The same molecule is also sold as Victoza, Xultophy — a separate application with its own approved uses and its own supply record, which is why the two are tracked apart here rather than merged. Its current FDA label, effective 2026-02-25, covers obesity. 1 presentation is currently listed on the FDA shortage database. It is also authorised in the EU, which does not always follow the US indication wording.

Saxenda and Victoza, Xultophy are the same molecule. They are marketed under separate FDA applications with different approved indications, so they are distinct products on the regulatory record even though the active ingredient is identical. Compare the applications below. Side by side: Saxenda vs Victoza · Saxenda vs Xultophy.

Active ingredient
liraglutide
Sponsor
Novo Nordisk
FDA applications
NDA206321
First FDA action
2014-12-23
Most recent FDA action
2026-06-02
FDA actions on file
20
EU authorisation
Saxenda
Active trials of liraglutide
17

Approved indications

Quoted from the current FDA label for each application. This is what the drug is approved to treat in the US — separate from the conditions it is being studied in.

Saxenda NDA206321
label effective 2026-02-25 · full label

SAXENDA is indicated in combination with a reduced calorie diet and increased physical activity to reduce excess body weight and maintain weight reduction long term in: • Adults and pediatric patients aged 12 years and older with body weight greater than 60 kg and obesity. • Adults with overweight in the presence of at least one weight-related comorbid condition. Limitations of Use • SAXENDA contains liraglutide. Coadministration with other liraglutide-containing products or with any other glucagon-like peptide-1 (GLP-1) receptor agonist is not recommended. • The safety and effectiveness of SAXENDA in pediatric patients with type 2 diabetes have not been established. SAXENDA is a glucagon like peptide 1 (GLP-1) receptor agonist indicated in combination with a reduced calorie diet and increased physical activity to reduce excess body weight and maintain weight reduction long term in: • Adults and pediatric patients aged 12 years and older with body weight greater than 60 kg and obesity. ( 1 ) • Adults with overweight in the presence of at least one weight-related comorbid condition. ( 1 ) Limitations of Use: • Coadministration with other liraglutide-containing products or with any other GLP-1 receptor agonist is not recommended. ( 1 ) • The safety and effectiveness of SAXENDA in pediatric patients with type 2 diabetes have not been established. ( 1 )

FDA record

Every approved submission filed under this brand, newest first, from Drugs@FDA: original approval, efficacy supplements, labeling changes and manufacturing updates. New safety language usually arrives in a labeling supplement.

DateActionApplication
2026-06-02LabelingNDA206321 · label
2026-02-25LabelingNDA206321 · label
2025-10-14LabelingNDA206321 · label
2025-05-28LabelingNDA206321 · label
2024-11-01LabelingNDA206321 · label
2023-04-20LabelingNDA206321 · label
2022-06-15LabelingNDA206321 · label
2020-12-04LabelingNDA206321 · label
2020-12-04EfficacyNDA206321 · label
2020-12-04LabelingNDA206321 · label
2020-03-25EfficacyNDA206321 · label
2018-12-04REMSNDA206321 · label
2018-10-19EfficacyNDA206321 · label
2017-05-22REMSNDA206321 · label
2017-04-26LabelingNDA206321 · label
2017-04-26EfficacyNDA206321 · label
2016-09-22LabelingNDA206321 · label
2016-02-01REMSNDA206321 · label
2015-03-27LabelingNDA206321 · label
2014-12-23Type 10 - New Indication Submitted as Distinct NDA - Not Consolidated originalNDA206321 · label

Supply records

FDA Drug Shortage Database entries naming this brand.

UpdatedStatusPresentationFDA note
08/25/2026CurrentSaxenda, Injection, 6 mg/1 mL (NDC 0169-2800-15)Product will be available until discontinuation in January 2027
08/25/2026To Be DiscontinuedSaxenda, Injection, 6 mg/1 mL (NDC 0169-2800-15)Product will be available until discontinuation in January 2027; Discontinuation of the manufacture of the drug

For the molecule behind this brand — every trial, every indication under study and the full research record — see liraglutide.