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Compare › Rybelsus vs Wegovy

Rybelsus vs Wegovy

Rybelsus and Wegovy are the same molecule — semaglutide. They are sold under separate FDA applications (NDA213051, NDA213182 and NDA215256, NDA218316), which is why they carry different approved indications, different labels and different supply records. On the regulatory record they are distinct products with an identical active ingredient.

Rybelsus Wegovy
Active ingredientsemaglutidesemaglutide
FDA applicationNDA213051, NDA213182NDA215256, NDA218316
First FDA action2019-09-202021-06-04
SponsorNovo NordiskNovo Nordisk
EU authorisationRybelsusWegovy
FDA supply status3 to be discontinuedNo open records
FDA actions on file1454
Active trials of the molecule203203

Everything above is a field from Drugs@FDA, the FDA Drug Shortage Database, the EMA register or ClinicalTrials.gov. There is no efficacy comparison here and there will not be one: head-to-head claims belong to the trials that made them, and which drug suits a particular person is a question for a clinician.

Full records: Rybelsus · Wegovy · semaglutide