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Trial results

Multi-Site Trial of Tirzepatide for Smoking Cessation

NCT07602699 on ClinicalTrials.gov · last registry update 2026-07-17

An unusually large phase 2: 300 participants, more than double the 114 typical for the stage. Due to report March 2028, alongside 22 other tracked readouts that quarter. Primary outcome, as filed: 7-day point prevalence abstinence. Sponsors move these dates routinely; any movement since this site started watching is listed below. tirzepatide is approved in the US, but not for substance use — a registration here is not an approval, and most drugs tested in a new condition never get one for it.

Status
RECRUITING
Phase
P2
Drug
tirzepatide
Zepbound, Mounjaro
Sponsor
University of Southern California
Sponsor type
Other
Enrollment
300
Started
2026-06-05
Primary completion
2028-03 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

7-day point prevalence abstinence

Conditions studied

Smoking Cessation · Smoking Behaviors

Every field above is taken directly from the registry record. See all detected changes across the class, or the tirzepatide page for this molecule’s full trial and approval history.