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Trial results

Efficacy and Safety of HDM1005 Compared to Tirzepatide in Obese Adults Without Diabetes

NCT07521631 on ClinicalTrials.gov · last registry update 2026-04-13

An unusually large phase 2: 372 participants, more than double the 114 typical for the stage. Due to report 4 February 2027, alongside 30 other tracked readouts that quarter. Primary outcome, as filed: Primary Outcome. Sponsors move these dates routinely; any movement since this site started watching is listed below. tirzepatide is already approved in the US for obesity, so this is asking a further question rather than establishing the drug works at all.

Status
RECRUITING
Phase
P2
Drug
tirzepatide
Zepbound, Mounjaro
Sponsor
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Sponsor type
Industry
Enrollment
372
Started
2026-03-31
Primary completion
2027-02-04 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Primary Outcome

Conditions studied

Obesity

Every field above is taken directly from the registry record. See all detected changes across the class, or the tirzepatide page for this molecule’s full trial and approval history.