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Trial results

A Study of HDM1005 in Participants With T2DM Not Controlled With Metformin Alone or in Combination With a Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor

NCT07417306 on ClinicalTrials.gov · last registry update 2026-02-18

An unusually large phase 3: 912 participants, more than double the 424 typical for the stage. Due to report 30 August 2027, alongside 39 other tracked readouts that quarter. Primary outcome, as filed: Change from baseline in Hemoglobin A1c (HbA1c). Sponsors move these dates routinely; any movement since this site started watching is listed below. mazdutide is not approved in the US for anything yet, so this is a drug in development rather than an established treatment being extended.

Status
NOT_YET_RECRUITING
Phase
P3
Drug
mazdutide
Sponsor
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Sponsor type
Industry
Enrollment
912
Started
2026-03-27
Primary completion
2027-08-30 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Change from baseline in Hemoglobin A1c (HbA1c)

Conditions studied

Type 2 Diabetes

Every field above is taken directly from the registry record. See all detected changes across the class, or the mazdutide page for this molecule’s full trial and approval history.