What happens next in GLP-1 — and when.

Trial results

A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)

NCT07247084 on ClinicalTrials.gov · last registry update 2026-09-09

An unusually large phase 4: 3,000 participants, more than double the 75 typical for the stage. Due to report July 2029, alongside 12 other tracked readouts that quarter. Primary outcome, as filed: Percent Change from Baseline in Body Weight. Sponsors move these dates routinely; any movement since this site started watching is listed below. tirzepatide is already approved in the US for obesity, so this is asking a further question rather than establishing the drug works at all.

Status
RECRUITING
Phase
P4
Drug
tirzepatide
Mounjaro, Zepbound
Sponsor
Eli Lilly and Company
Sponsor type
Industry
Enrollment
3,000
Started
2025-11-24
Primary completion
2029-07 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Percent Change from Baseline in Body Weight

Conditions studied

Obesity

Every field above is taken directly from the registry record. See all detected changes across the class, or the tirzepatide page for this molecule’s full trial and approval history.

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