What happens next in GLP-1 — and when.

Get the briefing

What moved in the GLP‑1 field, in your inbox.

@glp1briefing

Trial results

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

NCT07223593 on ClinicalTrials.gov · last registry update 2026-08-21

An unusually large phase 3: 1,205 participants, more than double the 424 typical for the stage. Due to report June 2028, alongside 27 other tracked readouts that quarter. Primary outcome, as filed: Percent Change from Baseline in Maximum Walking Distance. Sponsors move these dates routinely; any movement since this site started watching is listed below.

Status
RECRUITING
Phase
P3
Drug
orforglipron
Foundayo
Sponsor
Eli Lilly and Company
Sponsor type
Industry
Enrollment
1,205
Started
2025-10-31
Primary completion
2028-06 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Percent Change from Baseline in Maximum Walking Distance

Conditions studied

Peripheral Arterial Disease

Every field above is taken directly from the registry record. See all detected changes across the class, or the orforglipron page for this molecule’s full trial and approval history.