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Trial results

Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation

NCT07092618 on ClinicalTrials.gov · last registry update 2025-07-30

An unusually large phase 2/phase 3: 150 participants, more than double the 60 typical for the stage. Its estimated completion date, August 2025, has passed with no update to the record. A lapsed estimate is not a result and not a failure — sponsors are slow to refile — but ClinicalTrials.gov marks it nowhere on the record, so it is noted here.

Status
RECRUITING
Phase
P2/P3
Drug
semaglutide
Wegovy, Ozempic, Rybelsus
Sponsor
AgelessRx
Sponsor type
Industry
Enrollment
150
Started
2024-12-17
Primary completion
2025-08 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Evaluate the effectiveness of metformin in maintaining GLP1-induced weight loss in participants weaning off of Ozempic or Wegovy (or compounded semaglutide equivalent)

Conditions studied

Longevity · GLP-1 · Geroscience · Aging

Every field above is taken directly from the registry record. See all detected changes across the class, or the semaglutide page for this molecule’s full trial and approval history.