What happens next in GLP-1 — and when.

Trial results

Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer

NCT07078838 on ClinicalTrials.gov · last registry update 2026-09-28

A small phase 2 — 40 participants, against a typical 110. Due to report March 2029, alongside 11 other tracked readouts that quarter. Primary outcome, as filed: Anti-proliferative effect of Tirzepatide. Sponsors move these dates routinely; any movement since this site started watching is listed below. tirzepatide is approved in the US, but not for cancer — a registration here is not an approval, and most drugs tested in a new condition never get one for it.

Status
NOT_YET_RECRUITING
Phase
P2
Drug
tirzepatide
Mounjaro, Zepbound
Sponsor
UNC Lineberger Comprehensive Cancer Center
Sponsor type
Other
Enrollment
40
Started
2027-01
Primary completion
2029-03 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Anti-proliferative effect of Tirzepatide

Conditions studied

Endometrial Cancer · Endometrial Intraepithelial Neoplasia · Grade 1 Endometrial Endometrioid Carcinoma

Every field above is taken directly from the registry record. See all detected changes across the class, or the tirzepatide page for this molecule’s full trial and approval history.

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