What happens next in GLP-1 — and when.

Trial results

A Study of Tirzepatide (LY3298176) in Adult Participants With Type 2 Diabetes Switching From Dulaglutide (SURPASS-SWITCH)

NCT05564039 on ClinicalTrials.gov · last registry update 2025-08-03

An unusually large phase 4: 282 participants, more than double the 75 typical for the stage. The sponsor logged completion for 15 July 2024. Primary outcome, as filed: Change From Baseline in HbA1c. tirzepatide is already approved in the US for type 2 diabetes, so this is asking a further question rather than establishing the drug works at all.

Status
COMPLETED
Phase
P4
Drug
tirzepatide
Mounjaro, Zepbound
Sponsor
Eli Lilly and Company
Sponsor type
Industry
Enrollment
282
Started
2022-11-30
Primary completion
2024-07-15 actual

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Change From Baseline in HbA1c

Conditions studied

Type 2 Diabetes

Every field above is taken directly from the registry record. See all detected changes across the class, or the tirzepatide page for this molecule’s full trial and approval history.

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