What happens next in GLP-1 — and when.

Trial results

A Study of LY3437943 in Participants Who Have Obesity or Are Overweight

NCT04881760 on ClinicalTrials.gov · last registry update 2023-09-13

An unusually large phase 2: 338 participants, more than double the 110 typical for the stage. The sponsor logged completion for 16 May 2022. Primary outcome, as filed: Mean Percent Change From Baseline in Body Weight. retatrutide is not approved in the US for anything yet, so this is a drug in development rather than an established treatment being extended.

Status
COMPLETED
Phase
P2
Drug
retatrutide
Sponsor
Eli Lilly and Company
Sponsor type
Industry
Enrollment
338
Started
2021-05-20
Primary completion
2022-05-16 actual

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Mean Percent Change From Baseline in Body Weight

Conditions studied

Obesity · Overweight

Every field above is taken directly from the registry record. See all detected changes across the class, or the retatrutide page for this molecule’s full trial and approval history.

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