What happens next in GLP-1 — and when.

Trial results

Brain Activation and Satiety in Children 2

NCT04520490 on ClinicalTrials.gov · last registry update 2026-01-05

A small phase 3 — 63 participants, against a typical 424. The sponsor logged completion for 21 August 2025. Primary outcome, as filed: Change of BMI z-score. exenatide is approved in the US, but not for obesity — a registration here is not an approval, and most drugs tested in a new condition never get one for it.

Status
ACTIVE_NOT_RECRUITING
Phase
P3
Drug
exenatide
Bydureon, Byetta
Sponsor
Seattle Children's Hospital
Sponsor type
Other
Enrollment
63
Started
2021-01-28
Primary completion
2025-08-21 actual

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Change of BMI z-score

Conditions studied

Childhood Obesity

Every field above is taken directly from the registry record. See all detected changes across the class, or the exenatide page for this molecule’s full trial and approval history.

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