What happens next in GLP-1 — and when.

Trial results

Exendin-4 as a Treatment for Parkinson's Disease - Pilot Study

NCT01174810 on ClinicalTrials.gov · last registry update 2012-03-23

A small phase 2 — 40 participants, against a typical 110. Its estimated completion date, March 2013, has passed with no update to the record. A lapsed estimate is not a result and not a failure — sponsors are slow to refile — but ClinicalTrials.gov marks it nowhere on the record, so it is noted here. exenatide is approved in the US, but not for neurodegenerative — a registration here is not an approval, and most drugs tested in a new condition never get one for it.

Status
UNKNOWN
Phase
P2
Drug
exenatide
Bydureon, Byetta
Sponsor
University College, London
Sponsor type
Other
Enrollment
40
Started
2010-07
Primary completion
2013-03 estimated

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Change from baseline to 12 months & 14 months between patients on active Exenatide treatment and PD controls in respect of their UPDRS-off-medication motor subscore.

Conditions studied

Parkinson's Disease

Every field above is taken directly from the registry record. See all detected changes across the class, or the exenatide page for this molecule’s full trial and approval history.

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