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Trial results

A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight

NCT05929066 on ClinicalTrials.gov · last registry update 2026-08-21

An unusually large phase 3: 2,335 participants, more than double the 424 typical for the stage. The sponsor logged completion for 6 April 2026. Primary outcome, as filed: Percent Change From Baseline in Body Weight. retatrutide is not approved in the US for anything yet, so this is a drug in development rather than an established treatment being extended.

Status
COMPLETED
Phase
P3
Drug
retatrutide
Sponsor
Eli Lilly and Company
Sponsor type
Industry
Enrollment
2,335
Started
2023-07-10
Primary completion
2026-04-06 actual

Observed history

No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.

Primary outcome

Percent Change From Baseline in Body Weight

Conditions studied

Obesity · Overweight · Osteoarthritis, Knee · Obstructive Sleep Apnea

Every field above is taken directly from the registry record. See all detected changes across the class, or the retatrutide page for this molecule’s full trial and approval history.