A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease
NCT05882045 on ClinicalTrials.gov · last registry update 2026-07-30
An unusually large phase 3: 1,946 participants, more than double the 424 typical for the stage. The sponsor logged completion for 16 April 2026. Primary outcome, as filed: Percent Change from Baseline in Body Weight. retatrutide is not approved in the US for anything yet, so this is a drug in development rather than an established treatment being extended.
- Status
- COMPLETED
- Phase
- P3
- Drug
- retatrutide
- Sponsor
- Eli Lilly and Company
- Sponsor type
- Industry
- Enrollment
- 1,946
- Started
- 2023-05-30
- Primary completion
- 2026-04-16 actual
Observed history
No changes recorded since monitoring began on 2026-08-21. This record has held steady. If a reporting date moves, a status changes or enrollment is resized, it will appear here with the previous value alongside the new one.
Primary outcome
Percent Change from Baseline in Body Weight
Conditions studied
Obesity · Cardiovascular Diseases
Every field above is taken directly from the registry record. See all detected changes across the class, or the retatrutide page for this molecule’s full trial and approval history.